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ChemicalBook CAS DataBase List 2-[4-(TrifluoroMethoxy)phenyl]benzonitrile

2-[4-(TrifluoroMethoxy)phenyl]benzonitrile synthesis

4synthesis methods
611-20-1 Synthesis
2-Cyanophenol

611-20-1
542 suppliers
$6.00/5g

2-[4-(TrifluoroMethoxy)phenyl]benzonitrile

1365271-76-6
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: potassium phosphate / toluene; water / 0.5 h / 0 - 20 °C
2: XPhos; palladium diacetate / toluene / 24 h / 120 °C / Sealed tube; Inert atmosphere

References:

Zhou, Chao;Liu, Qingjiang;Li, Yaming;Zhang, Rong;Fu, Xinmei;Duan, Chunying [Journal of Organic Chemistry,2012,vol. 77,# 22,p. 10468 - 10472]