2-(5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)ETHAN-1-AMINE synthesis

4synthesis methods

Product Name:2-(5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)ETHAN-1-AMINE
CAS Number:3242-86-2
Molecular formula:C12H17N
Molecular Weight:175.27

2-Naphthalenecarboxylic acid, 5,6,7,8-tetrahydro-, methyl ester

23194-33-4
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2-(5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)ETHAN-1-AMINE

3242-86-2
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Yield:-

Steps:

Multi-step reaction with 4 steps
1: LiAlH₄ / diethyl ether / 1.5 h
2: MnO₂ / Ambient temperature
3: 10 N aq. NaOH / 2 h / Ambient temperature

References:

Francis, John E.;Webb, Randy L.;Ghai, Geetha R.;Hutchison, Alan J.;Moskal, Michael A.;et al. [Journal of Medicinal Chemistry,1991,vol. 34,# 8,p. 2570 - 2579]

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References

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5,6,7,8-Tetrahydronaphthalene-2-carboxaldehyde

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2-Naphthalenemethanol, 5,6,7,8-tetrahydro-

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References