2-(5-AMinopyridin-2-yl)acetonitrile synthesis

3synthesis methods

Product Name:2-(5-AMinopyridin-2-yl)acetonitrile
CAS Number:883993-15-5
Molecular formula:C7H7N3
Molecular Weight:133.15

123846-66-2
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883993-15-5
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Yield:883993-15-5 420 mg

Reaction Conditions:

with hydrogen in ethanol at 10 - 35; for 8 h;

Steps:

80.B B)
(5-aminopyridin-2-yl)acetonitrile

A mixture of (5-nitropyridin-2-yl)acetonitrile (930 mg), 3.5-6.5% palladium on carbon-ethylene diamine complex (93 mg) and EtOH (15 mL) was stirred under hydrogen atmosphere at room temperature for 8 hr.
The catalyst was removed by filtration, and the filtrate was concentrated under reduced pressure to give the title compound (420 mg).
MS: [M+H]⁺ 134.0.

References:

US2022/289679,2022,A1 Location in patent:Paragraph 0460-0461

4548-45-2 Synthesis

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References

914223-27-1 Synthesis

tert-butyl 2-cyano-2-(5-nitropyridin-2-yl)acetate

914223-27-1
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References

2-(5-AMinopyridin-2-yl)acetonitrile Related Search:

Acetonitrile