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2-(5-chloro-2-methyl-1H-indol-3-yl)ethanamine synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: trichlorophosphate / N,N-dimethyl-formamide
2: ammonium acetate
3: sodium tris(acetoxy)borohydride / tetrahydrofuran
4: palladium 10% on activated carbon; ammonium formate / methanol

References:

Baggett, Andrew W.;Cournia, Zoe;Han, Min Suk;Patargias, George;Glass, Adam C.;Liu, Shih-Yuan;Nolen, Brad J. [ChemMedChem,2012,vol. 7,# 7,p. 1286 - 1294]

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