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ChemicalBook CAS DataBase List 2,5-Dichloro-6-methyl-nicotinonitrile

2,5-Dichloro-6-methyl-nicotinonitrile synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: POCl3; PCl5
2: diethyl ether; SnCl2; concentrated aqueous HCl
3: aqueous CuSO4 / Diazotization

References:

Perez-Medina et al. [Journal of the American Chemical Society,1947,vol. 69,p. 2574,2577]