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ChemicalBook CAS DataBase List 2,5-Dichlorobenzoyl cyanide
64985-85-9

2,5-Dichlorobenzoyl cyanide synthesis

2synthesis methods
-

Yield:-

Steps:

4 EXAMPLE 4

EXAMPLE 4 132 g (0.5 mol) of 2,5-dichlorobenzoic acid anhydride, 105 g (0.5 mol) of 2,5-dichlorobenzoyl chloride and 32.5 g (0.5 mol) of potassium cyanide were slowly warmed to 150°-200° C. in a 500 ml flask, whilst stirring. The reaction was followed by IR spectroscopy. After conversion was complete, the mixture was subjected to fractional distillation (or, in the case of a further batch, to recrystallisation). Yield: 97 g (97% of theory) of 2,5-dichlorobenzoyl cyanide, boiling point 142°-145° C. at 15 mm Hg. 130 g (98.5% of theory of 2,5-dichlorobenzoic acid anhydride were recovered after the distillation.

References:

US4284584,1981,A

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