2-[(6-Chloro-2-pyridinyl)amino]-1-ethanol synthesis
- Product Name:2-[(6-Chloro-2-pyridinyl)amino]-1-ethanol
- CAS Number:29449-82-9
- Molecular formula:C7H9ClN2O
- Molecular Weight:172.61
2402-78-0
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29449-82-9
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$38.00/250mg
Yield:29449-82-9 99%
Reaction Conditions:
with pyridine at 20 - 100;
Steps:
67
Reference example 67: 2-(6-chloro-pyridin-2-ylaminoVethanol. 2-Arnino-ethanol (0.82 g, 13.5 mmol) was added to a solution of 2,6- dichloropyridine (2.0 g, 13.5 mmol) in pyridine (10 mL) at room temperature and then heated at 100 °C overnight The reaction mixture was concentrated in vacuo to obtain a residue which was dissolved in ethyl acetate. The solution was washed with water, brine, dried over anhydrous sodium sulfate and evaporated in vacuo to afford 2-(6- chloro-pyridin-2-ylamino)-ethanol (2.3 g, 99%) as a white solid.
References:
WO2008/62182,2008,A1 Location in patent:Page/Page column 128