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ChemicalBook CAS DataBase List 2,6-Dichloro-3-nitrobenzenesulfonamide
89281-19-6

2,6-Dichloro-3-nitrobenzenesulfonamide synthesis

2synthesis methods
-

Yield:89281-19-6 76%

Reaction Conditions:

with nitric acid in sulfuric acid;water;

Steps:

c c

c 2,6-dichloro-3-nitrobenzenesulfonamide Into a solution of 2,6-dichlorobenzenesulfonamide (7.8 g, 34.5 mmol) in 30 mL of concentrated sulfuric acid at 0°, nitric acid (1.74 mL, 41.4 mmol) was added dropwise. The mixture was stirred at 0° C. for 2 hours, then 200 mL of water was added to produce a precipitate. The resulting mixture was filtered. The white solid was collected, washed with water and dried in vacuo to give the desired product (7.17 g, 76%). 1H NMR (DMSO-d6): δ 8.25 (s, 2H), 8.20 (d, 1H), 7.92 (d, 1H).

References:

US2003/65170,2003,A1 US2003/65188,2003,A1