![](/CAS/GIF/5402-60-8.gif)
2,6-Dimethylbenzyl chloride synthesis
- Product Name:2,6-Dimethylbenzyl chloride
- CAS Number:5402-60-8
- Molecular formula:C9H11Cl
- Molecular Weight:154.64
![2,6-Dimethylbenzyl alcohol](/CAS/GIF/62285-58-9.gif)
62285-58-9
121 suppliers
$7.00/250mg
![2,6-Dimethylbenzyl chloride](/CAS/GIF/5402-60-8.gif)
5402-60-8
172 suppliers
$8.00/1g
Yield:5402-60-8 89.7%
Reaction Conditions:
with thionyl chloride
Steps:
16 Example 16
Example 16
2-(Chloromethyl)-1,3-dimethylbenzene
91.4 g [0.768 mol] of thionyl chloride in 100 ml of toluene are initially charged, heated to 72° C. and a solution of 100 g of 2,6-dimethylbenzyl alcohol of a purity of 74.7% in 700 ml of toluene is added dropwise thereto within an hour.
Further stirring is subsequently carried out for one hour at 72° C.
The excess thionyl chloride is distilled off, the residue is filtered over some Celite and concentrated under reduced pressure.
This gives 107.2 g of a brown oil which, according to GC/MS analysis, contains 71.0% of the title compound, which corresponds to a yield of 89.7% of theory.
GC/MS: m/e=154 (M+, 35Cl, 17%), 119 (M-35, 100%),
References:
US2021/403406,2021,A1
![Methyl 2,6-dimethylbenzoate](/CAS/GIF/14920-81-1.gif)
14920-81-1
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$27.00/250mg
![2,6-Dimethylbenzyl chloride](/CAS/GIF/5402-60-8.gif)
5402-60-8
172 suppliers
$8.00/1g
![2,6-Dimethylbenzaldehyde](/CAS/GIF/1123-56-4.gif)
1123-56-4
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$16.00/5g
![2,6-Dimethylbenzyl chloride](/CAS/GIF/5402-60-8.gif)
5402-60-8
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$8.00/1g
![2,6-Dimethylbenzoic acid](/CAS/GIF/632-46-2.gif)
632-46-2
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$10.00/1g
![2,6-Dimethylbenzyl chloride](/CAS/GIF/5402-60-8.gif)
5402-60-8
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$8.00/1g
![2,6-Dimethylaniline](/CAS/GIF/87-62-7.gif)
87-62-7
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$10.00/5G
![2,6-Dimethylbenzyl chloride](/CAS/GIF/5402-60-8.gif)
5402-60-8
172 suppliers
$8.00/1g