ChemicalBook CAS DataBase List 2,7-Dichlorofluorene

2,7-Dichlorofluorene synthesis

10synthesis methods

Product Name:2,7-Dichlorofluorene
CAS Number:7012-16-0
Molecular formula:C13H8Cl2
Molecular Weight:235.11

86-73-7 Synthesis

86-73-7
403 suppliers
$6.00/25g

7012-16-0
253 suppliers
$7.00/1g

Yield:7012-16-0 40.9%

Reaction Conditions:

with chlorine;acetic acid at 40; for 2 h;

Steps:

1 Example 1: Fluorene chloride
1200 mL of glacial acetic acid, 166.2 g (1 mol) of hydrazine (I) and a 2500 mL four-necked flask were maintained to maintain an internal temperature of 40 ° C.The chlorine gas was introduced under the right mechanical stirring, and the reaction was detected by high performance liquid chromatography until the basic reaction of 2-chloroindole was completed. Stop chlorine,Stir at 40 ° C for 2 h, warm to reflux until the reaction solution is completely soluble, cool to room temperature, filtered, solid 2,7-dichloropurine, after drying98 g, liquid phase content of 98.2% (0.409 mol), yield 40.9%. The mother liquor is a yellow transparent liquid, which is detected by liquid chromatography.The contents of the relevant components are shown in Table 1.

References:

Shaoxing University;Zhejiang Lai Yi Biological Co., Ltd.;Shen Runpu;Chen Weizhong;Shi Jiuhao;Liu Jian;Chang Kaikai;Qiu Jiangying;Shen Caiyun;Sheng Guodong;Feng Chengjie CN108586189, 2018, A Location in patent:Paragraph 0022-0025

FullText