ChemicalBook CAS DataBase List 2-ACETAMIDO-4-FLUOROANISOLE

2-ACETAMIDO-4-FLUOROANISOLE synthesis

5synthesis methods

Product Name:2-ACETAMIDO-4-FLUOROANISOLE
CAS Number:397-34-2
Molecular formula:C9H10FNO2
Molecular Weight:183.18

1978-39-8
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64-19-7 Synthesis

64-19-7
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$10.00/25ML

397-34-2
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Yield:397-34-2 99 %

Reaction Conditions:

with acetic anhydride at 0;Temperature;Time;

Steps:

1.3-3.3 (3) Synthesis of Compound V

Add 141g (1.0mol) of compound IV and 1500ml of acetic acid to the reaction flask, drop the temperature to 0°C and add 122.4g (1.2mol) of acetic anhydride dropwise, keep stirring for 5h after dripping, follow the reaction by HPLC until the reaction of compound IV is complete; add 1000ml of water to quench After the reaction was extinguished, a solid was precipitated, and 181.2 g of compound V was obtained by filtration and drying, with a molar yield of 99.0%.

References:

CN115417772,2022,A Location in patent:Paragraph 0030; 0036-0037; 0047; 0053-0054; 0062; 0068-0069

364-74-9 Synthesis