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2-AMINO-3-FLUORO-N-METHYL-BENZAMIDE synthesis

4synthesis methods
-

Yield:1017789-26-2 97 %

Reaction Conditions:

with N-ethyl-N,N-diisopropylamine;N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate in N,N-dimethyl-formamide at 20;

References:

Ashton, Trent D.;Dans, Madeline G.;Favuzza, Paola;Ngo, Anna;Lehane, Adele M.;Zhang, Xinxin;Qiu, Deyun;Chandra Maity, Bikash;De, Nirupam;Schindler, Kyra A.;Yeo, Tomas;Park, Heekuk;Uhlemann, Anne-Catrin;Churchyard, Alisje;Baum, Jake;Fidock, David A.;Jarman, Kate E.;Lowes, Kym N.;Baud, Delphine;Brand, Stephen;Jackson, Paul F.;Cowman, Alan F.;Sleebs, Brad E. [Journal of Medicinal Chemistry,2022]