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ChemicalBook CAS DataBase List 2-AMINO-4-(3,4-DIFLUOROPHENYL)THIAZOLE

2-AMINO-4-(3,4-DIFLUOROPHENYL)THIAZOLE synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: copper(ll) bromide / ethanol; chloroform; ethyl acetate / 0.5 h / 65 °C
2: ethanol / 2 h / Reflux

References:

Xu, Qinyuan;Huang, Li;Liu, Juan;Ma, Liang;Chen, Tao;Chen, Jinying;Peng, Fei;Cao, Dong;Yang, Zhuang;Qiu, Neng;Qiu, Jingxiang;Wang, Guangcheng;Liang, Xiaolin;Peng, Aihua;Xiang, Mingli;Wei, Yuquan;Chen, Lijuan [European Journal of Medicinal Chemistry,2012,vol. 52,p. 70 - 81]