2-AMINO-4-(4-NITROPHENYL)-3-FURONITRILE synthesis
- Product Name:2-AMINO-4-(4-NITROPHENYL)-3-FURONITRILE
- CAS Number:606099-85-8
- Molecular formula:C11H7N3O3
- Molecular Weight:229.19
64611-67-2
49 suppliers
$30.00/100mg
109-77-3
424 suppliers
$10.00/5g
606099-85-8
14 suppliers
inquiry
Yield:606099-85-8 80%
Reaction Conditions:
with diethylamine in methanol at 20; for 1 h;
Steps:
13B EXAMPLE 13B; 2-Amino-4-(4-nitrophenyl)-3-furonitrile
A mixture of Example 13A (5 g, 27.6 mmol) and malononitrile (2.74 g, 41.4 mmol) in methanol (8.6 mL) at room temperature was treated with diethylamine (1.43 mL, 13.8 mmol), stirred for 1 hour, and poured into water. The resulting suspension was filtered and the filter cake was washed with water then purified by flash column chromatography on silica gel with 1:1 ethyl acetate/hexanes to provide 5 g (80%) of the desired product. MS (DCI) m/e 247 (M+NH4)+
References:
US2003/225098,2003,A1 Location in patent:Page 32
64611-67-2
49 suppliers
$30.00/100mg
109-89-7
450 suppliers
$10.00/5g
109-77-3
424 suppliers
$10.00/5g
606099-85-8
14 suppliers
inquiry