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2-Amino-4,6-dimercaptopyrimidine synthesis

1synthesis methods
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Yield:626-49-3 98%

Reaction Conditions:

Stage #1: 2-Amino-4,6-dichloropyrimidinewith thiourea in ethanol; for 2 h;Reflux;
Stage #2: with water;sodium hydroxide at 80; for 16 h;

References:

Dolakova, Petra;Dracinsky, Martin;Masojidkova, Milena;Solinova, Veronika;Kasicka, Vaclav;Holy, Antonin [European Journal of Medicinal Chemistry,2009,vol. 44,# 6,p. 2408 - 2424] Location in patent:experimental part