2-AMINO-4-CHLORO-6-GUANIDINOPYRIMIDINE synthesis
1synthesis methods
- Product Name:2-AMINO-4-CHLORO-6-GUANIDINOPYRIMIDINE
- CAS Number:83170-03-0
- Molecular formula:C5H7ClN6
- Molecular Weight:186.6
Yield:-
Steps:
3 EXAMPLE 3
EXAMPLE 3 A mixture of 12.0 g (0.0732 m) of 2-amino-4,6-dichloropyrimidine and 55.0 g (0.931 mole) of guanidine was heated at 80° for 1.5 hours. The mixture was cooled to room temperature and diluted with water; the white crystalline precipitate was filtered, washed with water then air dried giving 7.22 g (53%) of 2-amino-6-chloro-4-guanidinopyrimidine, mp 220° (dec.). Anal. Calcd. for C5 H7 ClN6: C, 32.18; H, 3.78; N, 45.04. Found: C, 32.08; H, 3.97; N, 45.43.
References:
US4336254,1982,A