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ChemicalBook CAS DataBase List 2-AMINO-5-CHLORO-3-IODOBENZOIC ACID

2-AMINO-5-CHLORO-3-IODOBENZOIC ACID synthesis

2synthesis methods
-

Yield:64724-23-8 93%

Reaction Conditions:

Stage #1: methyl 2-amino-5-chloro-3-iodobenzoatewith sodium hydroxide in ethanol at 0; for 0.25 h;
Stage #2: with hydrogenchloride in water; pH=5;

References:

Zambaldo;Daguer;Saarbach;Barluenga;Winssinger [MedChemComm,2016,vol. 7,# 7,p. 1340 - 1351] Location in patent:supporting information