2-Amino-5-(trifluoromethoxy)biphenyl synthesis
1synthesis methods
- Product Name:2-Amino-5-(trifluoromethoxy)biphenyl
- CAS Number:131395-27-2
- Molecular formula:C13H10F3NO
- Molecular Weight:253.22
Yield:131395-27-2 92%
Reaction Conditions:
with bis-triphenylphosphine-palladium(II) chloride;potassium carbonate in water;N,N-dimethyl-formamide at 80; for 24 h;Inert atmosphere;Suzuki-Miyaura Coupling;
References:
Rajeshkumar, Venkatachalam;Chan, Fu-Wei;Chuang, Shih-Ching [Advanced synthesis and catalysis,2012,vol. 354,# 13,p. 2473 - 2483,11] Location in patent:supporting information