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ChemicalBook CAS DataBase List 2-benzoyl-N-(2-hydroxyethyl)-N-methylbenzamide
24833-47-4

2-benzoyl-N-(2-hydroxyethyl)-N-methylbenzamide synthesis

2synthesis methods
2-benzoyl-N-(2-hydroxyethyl)-N-methylbenzamide can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly in laboratory research and chemical production process.  It can be synthesized by the condensation reaction of 2-Methylaminoethanol and 2-Benzoylbenzoic acid.
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: thionyl chloride; N,N-dimethyl-formamide / 40 - 50 °C / Large scale
2: triethylamine / toluene / 0 - 30 °C / Large scale

References:

Bodireddy, Mohan Reddy;Krishnaiah, Kiran;Babu, Prashanth Kumar;Bitra, Chaithanya;Gajula, Madhusudana Rao;Kumar, Pramod [Organic Process Research and Development,2017,vol. 21,# 11,p. 1745 - 1751]

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