(2-Benzoylphenyl)(pyrrolidin-1-yl)methanone synthesis
- Product Name:(2-Benzoylphenyl)(pyrrolidin-1-yl)methanone
- CAS Number:31802-13-8
- Molecular formula:C18H17NO2
- Molecular Weight:279.33
Yield:31802-13-8 85%
Reaction Conditions:
with manganese oxide;carbon tetrabromide;sodium carbonate in toluene; for 12 h;Irradiation;
Steps:
5 Example 5
Add 32.46 parts of tetrabromomethane (97.0% content) to the 100.00Add 14.20 parts of tetrahydropyrrole to the reactor containing benzotrifluoride(Content is 99.0%), add 0.31 parts of trimanganese tetroxide (content is 99.5%)And 10.85 parts of sodium carbonate (99.8% content),Then add 45.70 parts of 2-benzoylbenzoic acid (99.0% content),Under the irradiation of the xenon lamp as the light source, after stirring and reacting for 12 hours,Distillation and recovery of trifluorotoluene solvent to obtain red and black oily bromineSimple substance and brownish yellow(2-Benzoylphenyl)(pyrrolidin-1-yl)methanone liquid product.
References:
CN112898233,2021,A Location in patent:Paragraph 0059-0062; 0093; 0094
