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ChemicalBook CAS DataBase List 2-Benzyl-4-bromoisoindoline

2-Benzyl-4-bromoisoindoline synthesis

3synthesis methods
-

Yield:923590-78-7 50%

Reaction Conditions:

with potassium carbonate in acetonitrile at 77 - 80; for 17 h;Inert atmosphere;

References:

McCauley, John A.;McIntyre, Charles J.;Rudd, Michael T.;Nguyen, Kevin T.;Romano, Joseph J.;Butcher, John W.;Gilbert, Kevin F.;Bush, Kimberly J.;Holloway, M. Katharine;Swestock, John;Wan, Bang-Lin;Carroll, Steven S.;Dimuzio, Julian M.;Graham, Donald J.;Ludmerer, Steven W.;Mao, Shi-Shan;Stahlhut, Mark W.;Fandozzi, Christine M.;Trainor, Nicole;Olsen, David B.;Vacca, Joseph P.;Liverton, Nigel J. [Journal of Medicinal Chemistry,2010,vol. 53,# 6,p. 2443 - 2463] Location in patent:experimental part