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ChemicalBook CAS DataBase List 2-(benzylamino)butan-1-ol

2-(benzylamino)butan-1-ol synthesis

4synthesis methods
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Yield:26020-80-4 71%

Reaction Conditions:

Stage #1: 2-aminobutanol;benzaldehyde in toluene; for 10 h;Molecular sieve;Inert atmosphere;Reflux;
Stage #2: with methanol;sodium tetrahydroborate at 0 - 20;Inert atmosphere;

References:

Hirano, Koji;Miura, Masahiro;Xu, Shibo [Organic Letters,2021,vol. 23,# 14,p. 5471 - 5475] Location in patent:supporting information