ChemicalBook CAS DataBase List 2-(BENZYLOXY)BENZAMIDE

2-(BENZYLOXY)BENZAMIDE synthesis

8synthesis methods

Product Name:2-(BENZYLOXY)BENZAMIDE
CAS Number:29579-11-1
Molecular formula:C14H13NO2
Molecular Weight:227.26

65-45-2 Synthesis

65-45-2
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$5.00/25g

29579-11-1
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$27.00/1g

Yield:29579-11-1 95%

Reaction Conditions:

with sodium hydroxide in ethanol; for 6 h;Reflux;

Steps:

3 5.1.4. General procedure for preparing 14a-c

General procedure: The mixture of 2-hydroxybenzamide (1 g, 7.3 mmol) and NaOH(0.4 g, 10 mmol) was stirred in EtOH (40 mL). Then, an appropriatealkyl halide (10.95 mmol) was added and the reaction medium wasrefluxed for 6 h. The excess of solvent was evaporated underreduced pressure, leading to a residue, which was triturated withwater, filtered and dried.

References:

Bouider, Nafila;Fhayli, Wassim;Ghandour, Zeinab;Boyer, Marjorie;Harrouche, Kamel;Florence, Xavier;Pirotte, Bernard;Lebrun, Philippe;Faury, Gilles;Khelili, Smail [Bioorganic and Medicinal Chemistry,2015,vol. 23,# 8,p. 1735 - 1746]

445-28-3 Synthesis