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107135-55-7

2-BroMo-3-iodo-1,4-diMethoxybenzene, 97% synthesis

4synthesis methods
25245-34-5 Synthesis
1-Bromo-2,5-dimethoxybenzene

25245-34-5
236 suppliers
$8.00/5g

2-BroMo-3-iodo-1,4-diMethoxybenzene, 97%

107135-55-7
6 suppliers
$67.20/1g

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Yield:107135-55-7 80%

Reaction Conditions:

Stage #1: 1-bromo-2,5-dimethoxybenzenewith lithium di-tert-butyl(2,2,6,6-tetramethylpiperidino)zincate in tetrahydrofuran at -78 - -30;
Stage #2: with iodine in tetrahydrofuran at -30 - 20;

References:

Guilarte, Veronica;Castroviejo, M. Pilar;Alvarez, Estela;Sanz, Roberto [Beilstein Journal of Organic Chemistry,2011,vol. 7,art. no. 146,p. 1255 - 1260] Location in patent:supporting information; experimental part