ChemicalBook CAS DataBase List 2-Bromo-4-methylbenzaldehyde

2-Bromo-4-methylbenzaldehyde synthesis

9synthesis methods

Product Name:2-Bromo-4-methylbenzaldehyde
CAS Number:824-54-4
Molecular formula:C8H7BrO
Molecular Weight:199.04

824-53-3
36 suppliers
$130.00/1g

824-54-4
134 suppliers
$12.00/1g

Yield:824-54-4 83%

Reaction Conditions:

with triphenylmethyl alcohol;iron(III) chloride hexahydrate at 55; for 1 h;Microwave irradiation;

Steps:

General procedures for the synthesis of benzaldehydes
General procedure: The benzyl alcohols substrates (1a-1p) (0.2mmol), FeCl₃·6H₂O (0.002mmol, 5.4mg) and triphenylmethanol 2 (0.2mmol, 52mg) were mixed in a dried vessel. Then the reaction was irradiated under the microwave at 55°C for 1h. The crude mixture was purified by a flash column chromatography to afford the benzaldehydes (4a-4p).

References:

Wang, Xiaoyu;Du, Chuan;Shi, Hui;Pang, Yadong;Jin, Shengfei;Hou, Yuqian;Wang, Yanshi;Peng, Xiaoshi;Xiao, Jianyong;Liu, Yang;Liu, Yongxiang;Cheng, Maosheng [Tetrahedron,2015,vol. 71,# 38,p. 6744 - 6748]

FullText