ChemicalBook CAS DataBase List 2-BROMO-5-PHENYLTHIOPHENE

2-BROMO-5-PHENYLTHIOPHENE synthesis

8synthesis methods

Product Name:2-BROMO-5-PHENYLTHIOPHENE
CAS Number:29488-24-2
Molecular formula:C10H7BrS
Molecular Weight:239.13

825-55-8
177 suppliers
$7.00/1g

29488-24-2
138 suppliers
$12.00/250mg

Yield:29488-24-2 100%

Reaction Conditions:

with N-Bromosuccinimide in chloroform at 20; for 0.5 h;

Steps:

1.2

The compoundA (1.5 g, 9.4 mmol) was completely dissolved in chloroform (100 mL), and then N-bromosuccinimide (1.7 g, 9.4 mmol) was slowly added thereto, followed by stirring at room temperature for 30 min. The solvent was completely removed by distillation under reduced pressure, and then ethanol was added thereto at O⁰C, followed by stirring for 20 min. The produced precipitate was filtered out, and then the filtrate was dried under vacuum at room temperature to give a compound B (2.2 g) with a yield of 100%.

References:

WO2008/153338,2008,A2 Location in patent:Page/Page column 30-31