![](/CAS/GIF/349120-88-3.gif)
2-BROMO-N-(2,5-DIMETHYL-PHENYL)-ACETAMIDE synthesis
- Product Name:2-BROMO-N-(2,5-DIMETHYL-PHENYL)-ACETAMIDE
- CAS Number:349120-88-3
- Molecular formula:C10H12BrNO
- Molecular Weight:242.11
![](/NewsImg/2022-07-14/6379340981057138924054572.jpg)
![2,5-Dimethylaniline](/CAS/GIF/95-78-3.gif)
95-78-3
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$10.00/1g
![Bromoacetyl bromide](/CAS/GIF/598-21-0.gif)
598-21-0
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$10.00/10g
![2-BROMO-N-(2,5-DIMETHYL-PHENYL)-ACETAMIDE](/CAS/GIF/349120-88-3.gif)
349120-88-3
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$45.00/50mg
Yield:349120-88-3 99%
Reaction Conditions:
with sodium carbonate in water; pH=9 - 10;
Steps:
4.6. General procedure for the synthesis of compounds 6a-o
General procedure: Computed amounts of alkyl/aralkyl/aryl amines (5a-o, 0.01 mol)were added separately in a quick fit Erlenmeyer flask already having20% aqueous Na2CO3 solution to set the pH 9-10. The bromoacetylbromide (0.01 mol) was added drop-wise into the flask over 2-5 minwith continuous vigorous shaking till the formation of precipitates followedby further stirring to get homogenous precipitates over a period of 1-2 h. The solid product was filtered, washed with cold water, and driedto get the respective electrophile(s), N-alkyl/aralkyl/aryl substituted-2-bromoacetamides (6a-o) and their names and physic-chemical constantsare as follows:
References:
Muzaffar, Saima;Shahid, Wardah;Riaz, Naheed;Saleem, Muhammad;Ashraf, Muhammad;Aziz-ur-Rehman;Bashir, Bushra;Kaleem, Ayesha;al-Rashida, Mariya;Baral, Bikash;Bhattarai, Keshab;Gross, Harald [Bioorganic Chemistry,2021,vol. 107,art. no. 104525]