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2-carboxymethyl-5-trifluoromethyl-benzoic acid synthesis
- Product Name:2-carboxymethyl-5-trifluoromethyl-benzoic acid
- CAS Number:207804-91-9
- Molecular formula:C10H7F3O4
- Molecular Weight:248.16
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1483-56-3
125 suppliers
$6.00/250mg
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141-97-9
796 suppliers
$5.00/25g
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207804-91-9
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Yield:207804-91-9 59%
Reaction Conditions:
Stage #1: 2-bromo-5-(trifluoromethyl)benzoic acid;ethyl acetoacetatewith sodium hydride;copper(I) bromide in mineral oil at 80; for 3.5 h;Sealed tube;Inert atmosphere;
Stage #2: with sodium hydroxide at 20; under 760.051 Torr; for 2 h;
References:
Trost, Barry M.;Kalnmals, Christopher A. [Chemistry - A European Journal,2018,vol. 24,# 36,p. 9066 - 9074] Location in patent:supporting information
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657-06-7
192 suppliers
$7.00/1g
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207804-91-9
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![Propanedioic acid, 2-[2-carboxy-4-(trifluoromethyl)phenyl]-, 1,3-dimethyl ester](/CAS/20210305/GIF/207804-90-8.gif)
207804-90-8
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207804-91-9
2 suppliers
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