ChemicalBook CAS DataBase List 2-Chloro-1,3-benzenedicarboxylic acid

2-Chloro-1,3-benzenedicarboxylic acid synthesis

6synthesis methods

Product Name:2-Chloro-1,3-benzenedicarboxylic acid
CAS Number:13049-16-6
Molecular formula:C8H5ClO4
Molecular Weight:200.58

6781-98-2 Synthesis

6781-98-2
156 suppliers
$9.00/5g

13049-16-6
39 suppliers
$25.00/100mg

15068-35-6
187 suppliers
$9.00/5g

Yield: 30%

Reaction Conditions:

with cobalt(II) acetate;acetic acid;sodium bromide at 95; under 760.051 Torr; for 6.7 h;

Steps:

4 Comparative example 4
In the reaction system, 140 g of raw material 2,6-dimethylchlorobenzene was added.Co(OAc)2 0.14g,NaBr 0.14g and 14g acetic acid,Warm the system to 95 ° C,Stir until the catalyst is completely dissolved.64 g of atmospheric pressure was introduced into the system for 6.7 h.Sampling test,Raw material 2,6-dimethylchlorobenzene 20%,The product 2-chloro-3-methylbenzoic acid is 40%,2,6-dicarboxychlorobenzene 30%,2-chloro-3-carboxybenzaldehyde 5%,2-chloro-3-methylbenzaldehyde 5%,The reaction solution was cooled to room temperature.After workup, the solid product 2-chloro-3-methylbenzoic acid is obtained.The yield was 30%.

References:

Lianhua Technology Co., Ltd.;Jiangsu Lianhua Technology Co., Ltd.;Lianhua Science And Technology (Yancheng) Co., Ltd.;Lianhua Science And Technology (Taizhou) Co., Ltd.;Lianhua Science And Technology (Texas) Co., Ltd.;Chen Jianguo;Guo Zhanghong;Jiang Peng;Chen Qingzhong;Yang Xiaomin CN108530297, 2018, A Location in patent:Paragraph 0103; 0104

6781-98-2 Synthesis

6781-98-2
156 suppliers
$9.00/5g

13049-16-6
39 suppliers
$25.00/100mg

References