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2-chloro-2-methylpropanamide synthesis

4synthesis methods
-

Yield:7462-75-1 38%

Reaction Conditions:

with ammonium hydroxide at -3; for 1 h;Inert atmosphere;Schlenk technique;

References:

Kanbayashi, Naoya;Takenaka, Kazuhiro;Okamura, Taka-Aki;Onitsuka, Kiyotaka [Angewandte Chemie - International Edition,2013,vol. 52,# 18,p. 4897 - 4901][Angew. Chem.,2013,vol. 125,# 18,p. 4997 - 5001,5] Location in patent:supporting information