2-CHLORO-3-(CHLOROMETHYL)-7-METHYLQUINOLINE synthesis

1synthesis methods

Product Name:2-CHLORO-3-(CHLOROMETHYL)-7-METHYLQUINOLINE
CAS Number:521915-96-8
Molecular formula:C11H9Cl2N
Molecular Weight:226.1

2-CHLORO-7-METHYL-3-QUINOLINECARBOXALDEHYDE

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2-CHLORO-3-(CHLOROMETHYL)-7-METHYLQUINOLINE

521915-96-8
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: sodium tetrahydroborate / ethanol / 20 °C
2: thionyl chloride / benzene / 80 °C

References:

Praveena, Koduru Sri Shanthi;Shivaji Ramarao, Edupuganti Veera Venkat;Murthy, Nandula Yadagiri Sreenivasa;Akkenapally, Surekha;Ganesh Kumar;Kapavarapu, Ravikumar;Pal, Sarbani [Bioorganic and Medicinal Chemistry Letters,2015,vol. 25,# 5,p. 1063 - 1069]

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