![](/CAS/GIF/15205-11-5.gif)
2-CHLORO-4-FLUOROBENZYLAMINE synthesis
- Product Name:2-CHLORO-4-FLUOROBENZYLAMINE
- CAS Number:15205-11-5
- Molecular formula:C7H7ClFN
- Molecular Weight:159.59
![2-Chloro-4-fluorobenzyl bromide](/CAS/GIF/45767-66-6.gif)
45767-66-6
201 suppliers
$8.00/10g
![2-CHLORO-4-FLUOROBENZYLAMINE](/CAS/GIF/15205-11-5.gif)
15205-11-5
154 suppliers
$8.00/1g
Yield:-
Reaction Conditions:
with ammonia in methanol at 50; for 2 h;Inert atmosphere;
Steps:
1 1-(2-Chloro-4-fluorophenyl)methanamine
To a stirred solution of 1-(bromomethyl)-2-chloro-4-fluorobenzene (1 g, 1 equiv.) in DMF (5 mL) was added NH3(g) in MeOH (5 mL) at room temperature under nitrogen atmosphere. The resulting mixture was stirred for 2 h at 50 degrees celsius under nitrogen atmosphere. The mixture was allowed to cool down to room temperature. The reaction was monitored by LCMS. The resulting mixture was used in the next step(E00848-157) directly without further purification
References:
WO2019/55966,2019,A2 Location in patent:Page/Page column 433; 434