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ChemicalBook CAS DataBase List 2-chloro-5,6,8-trimethoxyquinoline

2-chloro-5,6,8-trimethoxyquinoline synthesis

4synthesis methods
2(1H)-Quinolinone, 5,6,8-trimethoxy-

152531-86-7
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Yield:42065-10-1 88%

Reaction Conditions:

with pyridine;trichlorophosphate in N,N-dimethyl-formamide;chlorobenzene; for 3 h;Inert atmosphere;Reflux;

References:

Donohoe, Timothy J.;Jones, Christopher R.;Barbosa, Luiz C. A. [Journal of the American Chemical Society,2011,vol. 133,# 41,p. 16418 - 16421] Location in patent:supporting information; experimental part