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2-chloro-5-ethyl-1,3,4-thiadiazole synthesis

1synthesis methods
-

Yield:71859-81-9 79%

Reaction Conditions:

with hydrogenchloride;copper;sodium nitrite in water at -5 - 55;

References:

Cressier, Damien;Prouillac, Caroline;Hernandez, Pierre;Amourette, Christine;Diserbo, Michel;Lion, Claude;Rima, Ghassoub [Bioorganic and Medicinal Chemistry,2009,vol. 17,# 14,p. 5275 - 5284] Location in patent:experimental part