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ChemicalBook CAS DataBase List 2-cyano-N-(3-fluorophenyl)acetamide

2-cyano-N-(3-fluorophenyl)acetamide synthesis

2synthesis methods
-

Yield:1735-97-3 79%

Reaction Conditions:

with benzotriazol-1-ol;N-[3-(N,N-dimethylamino)-propyl]-N'-ethyl-carbodiimide hydrochloride;N-ethyl-N,N-diisopropylamine in dichloromethane at 25; for 18 h;

References:

Bae, Eun Jung;Jo, Heeji;Kim, Seong Soon;Shin, Dae-Seop;Yang, Jung Yoon;Bae, Myung Ae;Jeong, Pyeonghwa;Park, Chul-Seung;Ahn, Jin Hee [ACS Medicinal Chemistry Letters,2022,vol. 13,# 7,p. 1052 - 1061] Location in patent:supporting information