2-Cyclohexyl-benzene-1,3-diol synthesis
- Product Name:2-Cyclohexyl-benzene-1,3-diol
- CAS Number:30311-98-9
- Molecular formula:C12H16O2
- Molecular Weight:192.25
108-93-0
418 suppliers
$11.00/25g
108-46-3
749 suppliers
$10.00/10g
30311-98-9
8 suppliers
inquiry
2138-20-7
23 suppliers
$45.00/50mg
Yield:-
Reaction Conditions:
at 200; under 21446.5 Torr; for 2 h;Autoclave;Inert atmosphere;Reagent/catalyst;
Steps:
2.3. Experimental Procedure
Cyclohexylation of resorcinol with cyclohexanol was conductedin 100 ml Parr Autoclave (SS-316) in a batchmode. Known amounts of reactants and the catalyst weremixed and placed into the autoclave and was flushed withnitrogen with agitation prior to starting the reaction toensure the removal of dissolved air. The autoclave wasthen pressurized to 400 psig with nitrogen and stirred at800 rpm for all the experiments. The autoclave was heatedto the desired temperature and the reaction was initiated.A sample (zero hour) of the reaction mixture was keptfor analysis. After conducting the reaction for a fixed timeinterval, the autoclave was cooled to room temperatureand the reaction mixture was analysed for the conversionsof reactants and products distribution by Shimadzu14B gas chromatograph equipped with a flame ionizationdetector using SE-52 packed column. The identity of theproducts were confirmed by GC-MS (Shimadzu QP-5000).Based on the analysis, the percentage of conversion withrespect to either resorcinol or cyclohexanol and the distributionof products were calculated. Conversion of resorcinol (A) and Selectivity for the products (B) 3-Hydroxycyclohexyl phenyl ether; (C) 2-Cyclohexyl resorcinol and(D) 4-Cyclohexyl resorcinol present in the reaction mixturewere calculated as: Conversion of A, (wt.%) = [((wt.% of A)-(sum of the wt.% of B, C, and D)) /(wt.% of A)]×100 and Product selectivity (wt.%)= [((wt.% distribution of a product)/(sum of the wt.% of all the products)]×100.
References:
Balasubramanian;Devassay;Halligudi;Deepika;Umbarakar;Vinu [Journal of Nanoscience and Nanotechnology,2018,vol. 18,# 4,p. 2986 - 2992]
110-83-8
292 suppliers
$11.00/25g
108-46-3
749 suppliers
$10.00/10g
30311-98-9
8 suppliers
inquiry
2138-20-7
23 suppliers
$45.00/50mg
118163-40-9
3 suppliers
inquiry
118163-41-0
0 suppliers
inquiry
85586-52-3
1 suppliers
inquiry