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ChemicalBook CAS DataBase List 2-(Di-tert-butylphosphino)-2',6'-dimethoxybiphenyl
819867-21-5

2-(Di-tert-butylphosphino)-2',6'-dimethoxybiphenyl synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran / 1.75 h / 0 - 20 °C
1.2: 0.5 h / 0 °C
2.1: magnesium; ethylene dibromide / tetrahydrofuran / 1 h / 80 °C / Inert atmosphere
2.2: 18 h / 20 °C

References:

Golding, William A.;Pearce-Higgins, Robert;Phipps, Robert J. [Journal of the American Chemical Society,2018,vol. 140,# 42,p. 13570 - 13574]