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ChemicalBook CAS DataBase List 2-FLUORO-3-HYDROXYBENZALDEHYDE

2-FLUORO-3-HYDROXYBENZALDEHYDE synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 65 percent / imidazole / dimethylformamide
2: 1.) sec-butyllithium / 1.) THF, hexane, -78 deg C, 30 min, 2.) THF, hexane, -78 deg C, 5-10 min
3: Bu4NF / tetrahydrofuran; hexane / -78 - 20 °C

References:

Songca, Sandile P.;Bonnett, Raymond;Maes, Catherine M. [South African Journal of Chemistry,1997,vol. 50,# 1,p. 40 - 47]

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