2-FLUORO-3-(TETRAHYDRO-2H-PYRAN-4-YL)-PYRIDINE synthesis

3synthesis methods

Product Name:2-FLUORO-3-(TETRAHYDRO-2H-PYRAN-4-YL)-PYRIDINE
CAS Number:1227176-92-2
Molecular formula:C10H12FNO
Molecular Weight:181.21

Pyridine, 3-(3,6-dihydro-2H-pyran-4-yl)-2-fluoro-

1227176-91-1
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2-FLUORO-3-(TETRAHYDRO-2H-PYRAN-4-YL)-PYRIDINE

1227176-92-2
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Yield:1227176-92-2 96%

Reaction Conditions:

with 20% palladium hydroxide-activated charcoal;hydrogen at 20; for 4 h;Inert atmosphere;

References:

Hu, Essa;Chen, Ning;Bourbeau, Matthew P.;Harrington, Paul E.;Biswas, Kaustav;Kunz, Roxanne K.;Andrews, Kristin L.;Chmait, Samer;Zhao, Xiaoning;Davis, Carl;Ma, Ji;Shi, Jianxia;Lester-Zeiner, Dianna;Danao, Jean;Able, Jessica;Cueva, Madelyn;Talreja, Santosh;Kornecook, Thomas;Chen, Hang;Porter, Amy;Hungate, Randall;Treanor, James;Allen, Jennifer R. [Journal of Medicinal Chemistry,2014,vol. 57,# 15,p. 6632 - 6641]

287944-16-5 Synthesis

3,6-Dihydro-2H-pyran-4-boronic acid pinacol ester

287944-16-5
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1227176-92-2
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References

36178-05-9 Synthesis

36178-05-9
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$15.00/5g

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References