2-FLUORO-5-METHOXYBENZONITRILE synthesis
- Product Name:2-FLUORO-5-METHOXYBENZONITRILE
- CAS Number:127667-01-0
- Molecular formula:C8H6FNO
- Molecular Weight:151.14
796120-91-7
1 suppliers
inquiry
127667-01-0
187 suppliers
$10.00/1g
Yield: 11 g
Reaction Conditions:
with triethylamine;trifluoroacetic anhydride in tetrahydrofuran
Steps:
1.3 (3) Synthesis of 2-Fluoro-5-methoxybenzonitrile
15 g of 2-fluoro-5-methoxybenzaldehyde oxime was added to 150 ml of tetrahydrofuran,Add 40g of trifluoroacetic anhydride,Then add 20ml triethylamine,concentrate,Add water and ethyl acetate to extract,Collect the organic phase,dry,concentrate,The residue was separated on a silica gel column to give 11 g of 2-fluoro-5-methoxybenzonitrile.
References:
Hunan Huateng Pharmaceutical Co., Ltd.;Bu Gonggaofamingren CN107778264, 2018, A Location in patent:Paragraph 0029; 0030
67-56-1
774 suppliers
$7.29/5ml-f
179897-89-3
316 suppliers
$10.00/5g
127667-01-0
187 suppliers
$10.00/1g
459-60-9
362 suppliers
$7.00/5g
127667-01-0
187 suppliers
$10.00/1g
105728-90-3
174 suppliers
$12.00/1g
127667-01-0
187 suppliers
$10.00/1g
544-92-3
263 suppliers
$9.00/1g
202925-07-3
128 suppliers
$8.00/1g
127667-01-0
187 suppliers
$10.00/1g