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ChemicalBook CAS DataBase List 2-formyl-4-methoxybenzonitrile
21962-52-7

2-formyl-4-methoxybenzonitrile synthesis

7synthesis methods
7507-86-0 Synthesis
2-Bromo-5-methoxybenzaldehyde

7507-86-0
184 suppliers
$7.00/1g

2-formyl-4-methoxybenzonitrile

21962-52-7
6 suppliers
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: p-TsOH / toluene / 3 h / Heating
2: dimethylformamide / 1 h / Heating
3: 55 percent / 50percent aq. AcOH / 2 h / 100 °C

References:

Astles, Peter C.;Brown, Thomas J.;Halley, Frank;Handscombe, Caroline M.;Harris, Neil V.;McCarthy, Clive;McLay, Iain M.;Lockey, Peter;Majid, Tahir;Porter, Barry;Roach, Alan G.;Smith, Christopher;Walsh, Roger [Journal of Medicinal Chemistry,1998,vol. 41,# 15,p. 2745 - 2753]