2-heptylundecanol synthesis

Yield:-

Reaction Conditions:

with hydrogen at 125; under 15514.9 Torr; for 24 h;Pressure;Solvent;Time;Temperature;

Steps:

2 Example 2: Reduction of product from dimerization
Example 2: Reduction of product from dimerization [00103] 250 mL of nonanal (206 g, 1.45 mol) was dimerized according to the aforementioned conditions in Example 1, and the resulting dimer was separated from the ethanol and water layer. The dimer was then charged with 20% wt/wt Raney Nickel. The resulting mixture was placed in a high pressure reactor and was vigorously stirred under 300 psi of H₂ at 125 °C for 24 hours. The resulting material was then filtered to remove catalyst, yielding >90% pure desired product in >80% yield. NMR of the product was chararacterized by the disappearance of the enal protons and the appearance of 2 methylene protons at -3.3-3.5 ppm.

References:

P2 SCIENCE, INC.;FOLEY, Patrick;YANG, Yonghua WO2013/142206, 2013, A1 Location in patent:Paragraph 00103