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2-HEXYNYL-5'-N-ETHYLCARBOXAMIDOADANOSINE synthesis

8synthesis methods
β-D-Ribofuranuronic acid, 1-(6-amino-2-iodo-9H-purin-9-yl)-1-deoxy-, ethyl ester

141018-28-2
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2-HEXYNYL-5'-N-ETHYLCARBOXAMIDOADANOSINE

141018-30-6
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: 85 percent / -20 - 20 °C
2: 70 percent / triethylamine, cuprous iodide, PdCl2, triphenylphosphine / acetonitrile / 16 h / Ambient temperature

References:

Cristalli;Eleuteri;Vittori;Volpini;Lohse;Klotz [Journal of Medicinal Chemistry,1992,vol. 35,# 13,p. 2363 - 2368]