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2-Hydroxy-6-methyl-4-phenylpyridine synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: sodium hydride / mineral oil; hexane; acetonitrile
1.2: 5 h / 20 °C
2.1: potassium hydroxide / ethanol / 4 h / Reflux
3.1: sulfuric acid / ethanol / 30 h / Reflux

References:

Tohda, Yasuo;Yanagidani, Takeshi;Asaka, Noriko [Bulletin of the Chemical Society of Japan,2016,vol. 89,# 7,p. 810 - 822]