2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONE synthesis

5synthesis methods

Product Name:2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONE
CAS Number:6890-08-0
Molecular formula:C9H7NO3
Molecular Weight:177.16

611187-05-4 Synthesis

2-(benzyloxy)isoquinoline-1,3(2H,4H)-dione

611187-05-4
6 suppliers
inquiry

6890-08-0
32 suppliers
$65.00/100mg

Yield:6890-08-0 86%

Reaction Conditions:

Stage #1: 2-(benzyloxy)isoquinoline-1,3(2H,4H)-dionewith BBr₃ in dichloromethane at 20;
Stage #2: with lithium hydroxide monohydrate in dichloromethane at 20;

References:

Billamboz, Muriel;Bailly, Fabrice;Barreca, Maria Letizia;De Luca, Laura;Mouscadet, Jean-Fran?ois;Calmels, Christina;Andréola, Marie-Line;Witvrouw, Myriam;Christ, Frauke;Debyser, Zeger;Cotelle, Philippe [Journal of Medicinal Chemistry,2008,vol. 51,# 24,p. 7717 - 7730] Location in patent:experimental part

1,3(2H,4H)-Isoquinolinedione, 2-methoxy-

22367-15-3
3 suppliers
inquiry

6890-08-0
32 suppliers
$65.00/100mg

References

89-51-0
240 suppliers
$10.00/1g

6890-08-0
32 suppliers
$65.00/100mg

References

2446-51-7
35 suppliers
$45.00/50mg

6890-08-0
32 suppliers
$65.00/100mg

References

703-59-3
180 suppliers
$13.00/1g

6890-08-0
32 suppliers
$65.00/100mg

References