2-Iodo-4,4,5,5,5-pentafluoropent-1-ol synthesis
1synthesis methods
- Product Name:2-Iodo-4,4,5,5,5-pentafluoropent-1-ol
- CAS Number:757-06-2
- Molecular formula:C5H6F5IO
- Molecular Weight:304
Yield:757-06-2 600 g
Reaction Conditions:
with ammonium persulfate;sodium hydrogensulfite in water at 50 - 70;Reagent/catalyst;Temperature;
Steps:
3.1
(I) 110 g of propylene alcohol and 400 g of pentafluoroiodoethane were added to the autoclave, 50 g of ammonium persulfate was added,25g sodium bisulfite, add water 900ml, the control temperature is 50 ~ 70 , the reaction was stirred 4h ~ 8h. After the reaction was allowed to stand to separate the lower organic phase, the organic phase was washed with water and dried to give 4,4,5,5,5-pentafluoro-2-iodo-1-pentanol 600g.
References:
CN107501044,2017,A Location in patent:Paragraph 0028; 0030; 0032