![](/CAS/GIF/134272-64-3.gif)
2-MALEIMIDOETHYLAMINE HCL synthesis
- Product Name:2-MALEIMIDOETHYLAMINE HCL
- CAS Number:134272-64-3
- Molecular formula:C6H9ClN2O2
- Molecular Weight:176.6
![N-BOC-2-MALEIMIDOETHYLAMINE](/CAS/GIF/134272-63-2.gif)
134272-63-2
79 suppliers
$120.00/250 mg
![2-MALEIMIDOETHYLAMINE HCL](/CAS/GIF/134272-64-3.gif)
134272-64-3
146 suppliers
$26.00/100mg
Yield:134272-64-3 95.2%
Reaction Conditions:
with hydrogenchloride in ethyl acetate at 20; for 8 h;
Steps:
8 1-(2-Amino-ethyl)-pyrrole-2,5-dione Hydrochloride
N-(2-((tert-Butoxycarbonyl)amino)ethyl)maleimide (750 mg, 3.12 mmol) was dissolved in 4 M HCl in ethyl acetate (20 mL) and stirred for 8 h at room temperature. Then, addition of diethyl ether at 0 °C. provided the title compound as a white precipitate (524 mg, 2.97 mmol, 95.2% yield). 1H NMR (500 MHz, MeOD): δ 6.90 (s, 2H), 3.83-3.79 (m, 2H), 3.17-3.13 (m, 2H).
References:
HANGZHOU DAC BIOTECH CO., LTD.;SUN, Sanxing;ZHAO, Robert Yongxin;LI, Xing;GUO, Huihui;JIA, Junxiang;XIE, Hongsheng;ZHOU, Xiaomai;HUANG, Yuanyuan;YANG, Qingliang;ZHUO, Xiaotao;YE, Hangbo;GAI, Shun;QU, Lan;LI, Wenjun;LIN, Chen US2019/125894, 2019, A1 Location in patent:Paragraph 0162-0163