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2-methoxy-4,6-dimethylpyrimidine-5-carboxylic acid synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: CsCO3 / acetonitrile
2: NaOEt / ethanol / Heating
3: acidic solution

References:

McCombie, Stuart W.;Tagat, Jayaram R.;Vice, Susan F.;Lin, Sue-Ing;Steensma, Ruo;Palani, Anandan;Neustadt, Bernard R.;Baroudy, Bahige M.;Strizki, Julie M.;Endres, Michael;Cox, Kathleen;Dan, Niya;Chou, Chuan-Chu [Bioorganic and Medicinal Chemistry Letters,2003,vol. 13,# 3,p. 567 - 571]

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