2-Methyl-1,3-dioxolane-2-carbaldehyde synthesis

Yield:39050-39-0 70%

Reaction Conditions:

Stage #1: (2-methyl-[1,3]dioxolan-2-yl)-methanolwith dimethyl sulfoxide;dicyclohexyl-carbodiimide in diethyl ether at 20; for 0.25 h;Inert atmosphere;Moffatt type oxidation;
Stage #2: with pyridinium trifluroacetate in diethyl ether at 0 - 20; for 2.25 h;Inert atmosphere;

References:

Obringer, Michel;Barbarotto, Marie;Choppin, Sabine;Colobert, Francoise [Organic Letters,2009,vol. 11,# 16,p. 3542 - 3545] Location in patent:supporting information; experimental part