2-Methyl-2-(3-oxobutyl)cyclopentane-1,3-dione synthesis
4synthesis methods
- Product Name:2-Methyl-2-(3-oxobutyl)cyclopentane-1,3-dione
- CAS Number:25112-78-1
- Molecular formula:C10H14O3
- Molecular Weight:182.22
Yield:25112-78-1 95%
Reaction Conditions:
with triethylamine in dichloromethane; for 12 h;
Steps:
General procedure: Obtained by reaction of 2- methyl-1,3-cyclopentadione (2.2 g, 20 mmol) with methyl vinyl ketone (1.8 mL, 22 mmol) by the procedure described for the preparation of 8a. The pure compound was obtained as a colorless oil (3.5 g, 19 mmol, 95%). 1H-NMR (400 MHz, CDCl3): δ 1.04 (s, 3H); 1.79-1.83 (m, 2H); 2.03 (s, 3H); 2.39 (t, J = 7.2 Hz, 2H); 2.67-2.77 (m, 4H).
References:
Pedrosa, Rafael;Andrés, José María;Manzano, Rubén;Pérez-López, César [Tetrahedron Letters,2013,vol. 54,# 24,p. 3101 - 3104] Location in patent:supporting information
